How must pharmacies store Schedule II controlled substances?

• A. On open shelves.
• B. In a secured desk drawer without a lock.
• C. In a refrigerator.
• D. In a safe or locked cabinet.

Answer: (D)

Schedule II controlled substances must be kept in secure, locked storage to prevent theft and diversion. Regulatory requirements specify a securely locked cabinet or safe, or another locked location, with access restricted to authorized personnel. This level of security helps ensure accountability and reduces the risk of unauthorized dispensing. Storing these drugs on open shelves or in an unlocked desk drawer fails to meet the security standard, and refrigeration is not a universal requirement for all Schedule II substances—some may be stored at room temperature in a locked cabinet unless specific stability data call for refrigeration. Therefore, the proper storage is a safe or locked cabinet.